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Table 1 Clinical, laboratory and procedural characteristics of the overall study population, and of patients with normal (< 6%) and elevated (≥ 6%) hemoglobin A1c (HbA1c)

From: Impaired glucose metabolism is associated with increased thrombin generation potential in patients undergoing angioplasty and stenting

Characteristics

Overall (n = 315)

HbA1c < 6% (n = 156)*

HbA1c ≥ 6% (n = 145)*

p

Demographics

 Age, years

66 (58–75)

65 (57–74)

66 (58–75)

0.4

 Male sex

205 (65.1)

103 (66)

95 (65.5)

0.9

 BMI, kg/m2

26.8 (24.2–29.7)

26.2 (23.4–28.7)

27.3 (25.1–29.7)

0.007

Medical history

 Hypertension

283 (89.8)

135 (86.5)

134 (92.4)

0.1

 Hypercholesterolemia

293 (93)

144 (92.3)

136 (93)

0.6

 Diabetes mellitus

102 (32.4)

11 (7.1)

85 (58.6)

< 0.001

 Active smoking

132 (41.9)

76 (48.7)

53 (36.6)

0.03

Laboratory data

 HbA1c, %*

5.9 (5.6–6.5)

5.6 (5.4–5.8)

6.5 (6.1–7.2)

<0.001

 Hematocrit, %

38.9 (36–42)

39.6 (36.4–42.6)

38.7 (35.4–41.4)

0.1

 White blood cell count, G/l

8.4 (6.9–10.4)

8.2 (6.8–10.3)

8.7 (7–10.6)

0.3

 Platelet count, G/l

208 (176–251)

207 (173–249)

210 (177–259)

0.6

 Serum creatinine, mg/dl

1 (0.9–1.2)

1 (0.9–1.1)

1 (0.9–1.3)

0.2

 High-sensitivity CRP, mg/dl

0.8 (0.3–1.8)

0.9 (0.3–2.1)

0.8 (0.3–1.7)

0.4

Procedure

 Stent implantation

315 (100)

156 (100)

145 (100)

1

 Number of stents/patient

1 (1–2)

1 (1–2)

1 (1–2)

0.3

Medication pre-intervention

 Clopidogrel

315 (100)

156 (100)

145 (100)

1

 Aspirin

315 (100)

156 (100)

145 (100)

1

 Statins

300 (95.2)

149 (95.5)

139 (95.9)

0.9

 ACE inhibitors/ARB

272 (86.3)

135 (86.5)

124 (85.5)

0.8

 Beta blockers

216 (68.6)

104 (66.7)

105 (72.4)

0.3

 Proton pump inhibitors

165 (52.4)

75 (48.1)

81 (55.9)

0.2

 Antidiabetic medication

96 (30.5)

11 (7.1)

79 (54.5)

< 0.001

 Oral antidiabetic medication

77 (24.4)

8 (5.1)

67 (46.2)

< 0.001

 Insulin

30 (9.5)

3 (1.9)

23 (15.9)

< 0.001

  1. Continuous data are shown as median (interquartile range). Dichotomous data are shown as n (%)
  2. BMI body mass index, CRP c-reactive protein, ACE angiotensin converting enzyme, ARB angiotensin receptor blockers
  3. * HbA1c was only available for 301 patients (95.6%)