Fig. 6
From: MiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin
Gelsolin is a direct target of miR-21. a Relative mRNA levels detected by Ago2-RIP in treated H9c2 cells. b Relative mRNA levels detected by Ago2-RIP in treated HL-1 cells. c Relative mRNA levels detected by Ago2-RIP in treated human cardiac myocytes. d Schematic diagram of the luciferase reporter plasmids. e Regulation of miR-21 on 3′ UTR of GSN in HEK293 cells detected by luciferase reporter assays. f Protein levels of GSN in treated H9c2 cells. g Protein levels of GSN in treated mice