Table 4 Relationships between echocardiographic variables and baseline characteristics in controls, results from univariable and multivariable regression analysis
Explanatory variable | LV mass | LVEF | GLS | E/é | ||||
|---|---|---|---|---|---|---|---|---|
Univariable | Multivariable model R2 = 0.19 | Univariable | Multivariable model R2 = 0.09 | Univariable | Multivariable model R2 = 0.16 | Univariable | Multivariable model R2 = 0.22 | |
β1, R2 | B | β1, R2 | B | β1, R2 | B | β1, R2 | B | |
Demographic data | ||||||||
Age, years | 0.4, 0.01 | − 0.03, 0.00 | 0.02, 0.00 | 0.21***, 0.12 | 0.2*** | |||
Gender = female | − 15.0***, 0.11 | − 10.9** | 1.9, 0.02 | − 1.5**, 0.05 | − 1.0 | 0.5, 0.00 | 1.5** | |
Smoker/former smoker | 2.1, 0.00 | − 0.03, 0.00 | 0.38, 0.01 | 0.20, 0.00 | ||||
BMI, kg/m2 | 0.8, 0.21 | − 0.56***, 0.08 | − 0.6*** | 0.27***, 0.01 | 0.2*** | 0.26***, 0.08 | ||
Medical history | ||||||||
Angina pectoris | 2.9, 0.00 | − 1.0, 0.00 | − 0.85, 0.00 | 3.2, 0.02 | ||||
Myocardial infarction | 11.4, 0.01 | − 2.0, 0.00 | 1.2, 0.00 | − 0.46, 0.00 | ||||
Coronary revascularization | 10.1, 0.00 | 0.8, 0.00 | − 0.49, 0.00 | − 3.3*, 0.02 | ||||
Hypertension | 10.4*, 0.04 | − 1.9, 0.01 | 0.86, 0.01 | 0.50, 0.00 | ||||
Medication | ||||||||
Statins | 12.6*, 0.03 | 12.9* | − 3.3, 0.02 | 1.1, 0.01 | − 0.02, 0.00 | |||
ACEI and/or ARB | 8.3, 0.02 | − 2.2, 0.01 | 1.2, 0.01 | − 0.44, 0.00 | ||||
Calcium channel blocker | 15.6*, 0.03 | 0.5, 0.00 | − 0.81, 0.00 | 0.53, 0.00 | ||||
β-Blocker | 5.6, 0.01 | − 1.0, 0.00 | 0.55, 0.00 | 0.13, 0.00 | ||||
Laboratory analyses | ||||||||
Triglycerides, mmol/L | 0.9, 0.00 | 0.06, 0.00 | 0.01*, 0.00 | − 13, 0.00 | ||||
LDL-C, mmol/L | − 1.9, 0.00 | 0.34, 0.00 | 0.36, 0.01 | 0.40, 0.01 | ||||
Microalbuminuria | 10.5, 0.01 | − 14.8, 0.00 | 11.3, 0.00 | 3.5*, 0.04 | ||||
Creatinine, µmol/L | 0.3*, 0.03 | − 0.08, 0.00 | 0.09, 0.02 | 0.05, 0.01 | ||||
GFR, mL/min/1.73 m2 | 0.1, 0.00 | 0.04, 0.01 | 0.00, 0.00 | − 0.03, 0.02 | ||||
Blood pressure (mmHg) | ||||||||
Systolic blood pressure | 0.4***, 0.09 | 0.3** | − 0.03, 0.01 | 0.02, 0.01 | 0.06***, 0.09 | |||
Diastolic blood pressure | 0.6**, 0.08 | − 0.1, 0.02 | 0.08***, 0.07 | 0.2** | 0.10***, 0.08 | 0.1*** | ||