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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Glucose-sensing microRNA-21 disrupts ROS homeostasis and impairs antioxidant responses in cellular glucose variability

Fig. 6

Experimentally validated target genes of miR-21 and related pathways in HUVECs. a Number of miR-21 binding sites specifically evaluated in HUVECs by the extrapolation of experimentally supported (direct method: HITS-CLIP) [60] miRNA targets from DIANA-TarBase v8.0. b Analysis of target (proteins) network using STRING v10.5 (https://string-db.org): green line—neighbourhood evidence; blue line—co-occurrence evidence; purple line—experimental evidence; light blue line—database evidence; black line—co-expression evidence

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Cardiovascular Diabetology

ISSN: 1475-2840