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Table 2 Association of NOS3, ANGPTL8 and CETP SNPs with T2DM

From: Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease

Gene SNP Cases MAF Controls MAF p OR (95% CI)
NOS3 rs1799983 21.4 8.0 < 0.0001* 3.07 (1.82–5.19)
ANGPTL8 rs2278426 16 7.4 0.001* 2.33 (1.33–4.08)
CETP rs708272 33 41 0.05 0.7 (0.49–1.00)
  1. MAF minor allele frequency (defined based on frequency in controls)
  2. * Significant p
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Cardiovascular Diabetology

ISSN: 1475-2840