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Table 2 Association of NOS3, ANGPTL8 and CETP SNPs with T2DM

From: Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease

Gene

SNP

Cases MAF

Controls MAF

p

OR (95% CI)

NOS3

rs1799983

21.4

8.0

< 0.0001*

3.07 (1.82–5.19)

ANGPTL8

rs2278426

16

7.4

0.001*

2.33 (1.33–4.08)

CETP

rs708272

33

41

0.05

0.7 (0.49–1.00)

  1. MAF minor allele frequency (defined based on frequency in controls)
  2. * Significant p
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Cardiovascular Diabetology

ISSN: 1475-2840