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Table 4 Mean common carotid artery IMT, internal diameter (ID), and velocities (SPV: systolic peak velocity; EDV: end diastolic velocity; MV: mean velocity) measured at baseline, 1-month visit and 3-month visit

From: Empagliflozin influences blood viscosity and wall shear stress in subjects with type 2 diabetes mellitus compared with incretin-based therapy

 

Empagliflozin group

Control group

Baseline

1-month

3-month

p

Baseline

1-month

3-month

p

Number

40

40

40

–

30

30

30

–

ID R (mm)

5.9 ± 0.9¥

5.8 ± 0.8

5.8 ± 0.8

0.02

6.0 ± 0.8

5.9 ± 0.8

6.0 ± 0.7

NS

IDT (mm)

6.5 ± 0.9¥

6.3 ± 0.8

6.3 ± 0.9

0.02

6.6 ± 0.7

6.5 ± 0.9

6.6 ± 0.8

NS

Mean IMT (ÎĽm)

831 ± 156^*

793 ± 150

766 ± 127

0.0001

890 ± 146§

881 ± 160

841 ± 109

0.01

SPV (cm/s)

81 ± 18

83.6 ± 18

80 ± 13

NS

77 ± 18

77 ± 17

80 ± 18

NS

EDV (cm/s)

25 ± 6

25 ± 6

24 ± 4

NS

24 ± 6

27 ± 5

24 ± 8

NS

MV (cm/s)

41 ± 8

41 ± 4

39 ± 6

NS

38 ± 7

41 ± 2

40 ± 10

NS

  1. Bonferroni post hoc test: * vs 1-month p = 0.03; ^ vs 3-month p = 0.002; § vs 3-month p = 0.03; ¥ vs 1-month p = 0.04