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Table 3 Proportion and odds ratios (ORs) of DPN according to M-HbA1c tertiles (95% CI)

From: HbA1c variability and diabetic peripheral neuropathy in type 2 diabetic patients

 

M-HbA1c tertiles

p for trend

T1 (≤ 8.42%)

T2 (8.43%–9.33%)

T3 (≥ 9.34%)

n

188

188

187

–

DPN, n (%)

18 (9.6)

32 (17.0)

52 (27.8)

< 0.001

Model 1

1-reference

1.94 (1.05–3.59)

3.64 (2.03–6.51)

< 0.001

Model 2

1-reference

1.91 (1.02–3.53)

3.55 (1.96–6.40)

< 0.001

Model 3

1-reference

3.77 (1.61–8.84)

5.84 (2.49–13.64)

< 0.001

Model 4

1-reference

3.47 (1.42–8.50)

3.76 (1.41–9.98)

< 0.001

Model 5

1-reference

3.63 (1.45–9.09)

4.05 (1.49–11.01)

< 0.001

  1. Model 1: unadjusted model
  2. Model 2: adjusted for age, female ratio, body mass index, systolic/diastolic BP
  3. Model 3: additionally adjusted for diabetic duration, smoking, drinking, statins medications, hypertension and hypoglycaemia
  4. Model 4: additionally adjusted for serum uric acid, lipid profile, HOMA-IR, initial HbA1c, CV-HbA1c and UACR
  5. Model 5: additionally adjusted for hypoglycemic treatments