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Table 3 Proportion and odds ratios (ORs) of DPN according to M-HbA1c tertiles (95% CI)

From: HbA1c variability and diabetic peripheral neuropathy in type 2 diabetic patients

  M-HbA1c tertiles p for trend
T1 (≤ 8.42%) T2 (8.43%–9.33%) T3 (≥ 9.34%)
n 188 188 187
DPN, n (%) 18 (9.6) 32 (17.0) 52 (27.8) < 0.001
Model 1 1-reference 1.94 (1.05–3.59) 3.64 (2.03–6.51) < 0.001
Model 2 1-reference 1.91 (1.02–3.53) 3.55 (1.96–6.40) < 0.001
Model 3 1-reference 3.77 (1.61–8.84) 5.84 (2.49–13.64) < 0.001
Model 4 1-reference 3.47 (1.42–8.50) 3.76 (1.41–9.98) < 0.001
Model 5 1-reference 3.63 (1.45–9.09) 4.05 (1.49–11.01) < 0.001
  1. Model 1: unadjusted model
  2. Model 2: adjusted for age, female ratio, body mass index, systolic/diastolic BP
  3. Model 3: additionally adjusted for diabetic duration, smoking, drinking, statins medications, hypertension and hypoglycaemia
  4. Model 4: additionally adjusted for serum uric acid, lipid profile, HOMA-IR, initial HbA1c, CV-HbA1c and UACR
  5. Model 5: additionally adjusted for hypoglycemic treatments