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Table 1 Clinical characteristics in control subjects with normal glucose tolerance (NGT), type 2 diabetes (T2DM) patients without atherosclerosis, and T2DM patients with atherosclerosis

From: Triglyceride-mediated influence of serum angiopoietin-like protein 8 on subclinical atherosclerosis in type 2 diabetic patients: results from the GDMD study in China

Characteristics Control subjects with NGT (n = 100) T2DM without atherosclerosis (n = 100) T2DM with atherosclerosis (n = 100) P value
Age (years) 56.4 ± 7.6 56.2 ± 8.4 57.2 ± 7.7 0.628
Percent men (%) 54 56 49 0.593
Body mass index (kg/m2) 24.7 ± 3.7 24.4 ± 3.0 25.0 ± 3.6 0.400
Current smoking (%) 21 23 25 0.798
Habitual alcohol drinking (%) 26 22 28 0.611
Leisure-time physical activity (%) 67 52 49 0.023
Statin use (%) 14 32 42 < 0.001
NSAID use (%) 5 34 38 < 0.001
SBPa 132 ± 15 134 ± 18 134 ± 13 0.398
DBPa 72 ± 9 75 ± 11 74 ± 12 0.068
TG (mmol/L)a 1.31 (0.92,1.77) 1.62 (1.07,2.50) 2.04 (1.26,3.41) < 0.001
TC (mmol/L)a 4.83 ± 0.90 5.10 ± 0.85 4.94 ± 1.09 0.088
LDL-C (mmol/L)a 2.88 ± 0.69 3.08 ± 1.06 3.16 ± 0.89 0.082
HDL-C (mmol/L)a 1.23 ± 0.33 1.16 ± 0.41 1.19 ± 0.33 0.306
Fasting plasma glucose (mmol/L) 4.83 ± 0.63 8.62 ± 1.70 8.09 ± 1.64 < 0.001
Fasting insulin (μU/mL) 6.32 (5.17,8.77) 8.43 (7.09,10.88) 7.83 (5.99,11.06) < 0.001
HOMA-IR 1.41 (1.05, 1.93) 3.23 (2.45, 4.33) 2.92 (2.13, 3.73) < 0.001
Duration of diabetes (years) 6.7 ± 3.1 7.7 ± 4.4 < 0.001
HbA1c (%)a 5.1 ± 0.4 7.8 ± 1.3 7.7 ± 1.0 < 0.001
HbA1c (mmol/mol)a 32.6 ± 4.1 62.0 ± 14.1 60.4 ± 10.7 < 0.001
c-IMT (mm)a 0.54 ± 0.08 0.74 ± 0.09 0.90 ± 0.14 < 0.001
ANGPTL8a (pg/mL) 731 ± 285 1360 ± 310 1585 ± 555 < 0.001
  1. Data were expressed as mean ± standard deviation, median (interquartile range), or percentage for continuous various and categorical variables, respectively. Cigarette smoking was defined as having smoked at least 100 cigarettes in one’s lifetime. Regular leisure-time physical activity was defined as participation in ≥ 30 min of moderate or vigorous activity per day at least 3 days per week
  2. aAdjusted for age, gender, and BMI