Table 1 Clinical characteristics of all the patients by Hp genotype

N

377

2027

2834

133

306

10

–

Age (years)

60.71 ± 11.41

59.21 ± 12.21

59.86 ± 12.27

61.10 ± 11.53

58.52 ± 13.59

57.83 ± 9.17

0.0880

Male/female (n)

217/160

1110/917

1493/1341

80/53

173/133

5/5

0.1154

BMI (kg/m²)

24.71 ± 3.31

24.94 ± 5.52

24.69 ± 3.64

24.83 ± 3.26

24.67 ± 3.80

24.85 ± 1.87

0.5326

Diastolic blood pressure (mmHg)

80 (70, 86)

80 (75, 88)

80 (75, 88)

80 (70, 90)

80 (75, 85)

80 (70, 85)

0.1924

Systolic blood pressure (mmHg)

130 (120, 141)

130 (120, 140)

130 (120, 142)

130 (120, 145)

130 (120, 140)

120 (120, 140)

0.6499

Duration of diabetes (years)

7 (3, 12)

8 (3, 12)

8 (3, 13)

10 (4, 14)

9 (2, 13)

7 (3, 12)

0.4813

HbA1c (%) [mmol/mol]

8.8 (7.2, 10.5) [73 (55, 91)]

8.7 (7.3, 10.4) [72 (56, 90)]

8.6 (7.1, 10.4) [71 (54, 90)]

8.4 (6.9, 10.1) [68 (52, 87)]

8.8 (7.3, 10.4) [73 (56, 90)]

9.1 (6.9, 9.9) [76 (52, 85)]

0.6758

HDL-C (mmol/L)

1.07 (0.89, 1.29)

1.07 (0.90, 1.29)

1.09 (0.92, 1.30)

1.09 (0.91, 1.30)

1.10 (0.91, 1.27)

1.17 (1.09, 1.30)

0.0931

LDL-C (mmol/L)

2.86 (2.31, 3.41)

2.89 (2.31, 3.45)

2.97 (2.42, 3.58)

2.92 (2.34, 3.68)

3.08 (2.43, 3.81)

3.10 (2.33, 3.51)

< 0.0001

Total cholesterol (mmol/L)

4.60 (3.87, 5.40)

4.60 (3.94, 5.30)

4.70 (4.10, 5.47)

4.67 (4.00, 5.50)

4.80 (4.18, 5.63)

4.82 (3.60, 5.30)

< 0.0001

Triglycerides (mmol/L)

1.41 (0.98, 2.10)

1.41 (0.96, 2.13)

1.44 (1.00, 2.13)

1.49 (0.97, 1.88)

1.47 (1.00, 2.01)

1.17 (1.09, 1.36)

0.5292

Macroangiopathy disease

296 (78.51%)

1471 (72.57%)

2052 (72.41%)

105 (78.95%)

222 (72.55%)

7 (70.00%)

0.0793