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Table 2 Univaraite and multivariate analyses for new-onset diabetes mellitus

From: Increased epicardial adipose tissue thickness is a predictor of new-onset diabetes mellitus in patients with coronary artery disease treated with high-intensity statins

Factor

Univariate analysis

Multivariate analysis

HR (95% CI)*

P value

HR (95% CI)*

P value

Age

0.999 (0.975–1.023)

0.909

0.978 (0.950–1.007)

0.130

Male sex

1.029 (0.502–2.108)

0.938

1.220 (0.539–2.765)

0.633

BMI

1.062 (0.956–1.179)

0.263

0.996 (0.877–1.131)

0.996

Diagnosis as acute coronary syndrome

0.954 (0.497–1.830)

0.888

–

–

Hypertension

1.524 (0.818–2.838)

0.184

1.727 (0.872–3.420)

0.117

Current smoking

1.030 (0.503–2.109)

0.935

–

–

Dyslipidemia

1.114 (0.530–2.341)

0.775

–

–

Prediabetes at baseline

5.503 (2.619–11.564)

< 0.001

4.321 (1.998–9.349)

< 0.001

Anemia (Hemoglobin < 12 g/dL)

2.745 (0.377–19.985)

0.319

–

–

TG level (per mg/dL)

1.001 (0.999–1.004)

0.309

–

–

LDL-cholesterol level (per mg/dL)

1.002 (0.993–1.011)

0.703

–

–

LV ejection fraction < 40%

2.153 (0.296–15.672)

0.449

–

–

EAT thickness at diastole (per mm)

1.625 (1.353–1.950)

< 0.001

  

EAT thickness at systole (per mm)

1.611 (1.388–1.870)

< 0.001

1.580 (1.346–1.854)

< 0.001

Total statin duration (per year)

0.916 (0.716–1.171)

0.482

0.876 (0.733–1.048)

0.147

High intensity statin duration

0.989 (0.804–1.217)

0.918

–

–

  1. BMI body mass index, LV left ventricle, LDL low density lipoprotein, TG triglyceride, EAT epicardial adipose tissue
  2. * The hazard ratio (HR) along with its corresponding 95% confidence interval (CI) and p values are based on Cox proportional hazard analysis