| Hazard ratio (95% CI); P value | |
---|---|---|
Univariate | Multivariate | |
DPP4i versus other hypoglycemic agents | 0.65 (0.56–0.76); < 0.0001 | 0.69 (0.59–0.81); P < 0.0001 |
Age (years) | ||
 < 65 | 1.00 (reference) | 1.00 (reference) |
 ≥ 65 | 5.76 (4.97–6.68); < 0.0001 | 4.75 (4.07–5.55); P < 0.0001 |
Female gender | 0.87 (0.75–1.01); 0.0714 |  |
Chronic lung disease | 2.28 (1.46–3.56); 0.0003 |  |
Chronic kidney disease | 1.74 (1.37–2.21); < 0.0001 |  |
Hypertension | 2.64 (2.22–3.13); < 0.0001 | 1.74 (1.45–2.06); P < 0.0001 |
Ischemic heart disease | 3.84 (2.88–5.13); < 0.0001 | 1.98 (1.48–2.66); P < 0.0001 |