The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis

Table 3 Correlation of the neointimal and medial areas with the number of proliferating and total cells

Neointimal area	r	p	Medial area	r	p
Combined			Combined
Intima			Intima
Ki67+ cells	0.48	< 0.0001	Ki67+ cells	0.04	0.73
Total cells	0.85	< 0.0001	Total cells	− 0.44	< 0.01
Media			Media
Ki67+ cells	− 0.20	0.12	Ki67+ cells	− 0.30	0.02
Total cells	− 0.21	0.10	Total cells	0.45	< 0.01
Vehicle alone			Vehicle alone
Intima			Intima
Ki67+ cells	0.68	< 0.01	Ki67+ cells	0.09	0.70
Total cells	0.92	< 0.0001	Total cells	− 0.31	0.19
Media			Media
Ki67+ cells	− 0.07	0.79	Ki67+ cells	0.00	0.99
Total cells	0.13	0.60	Total cells	0.46	0.04
Liraglutide alone			Liraglutide alone
Intima			Intima
Ki67+ cells	0.61	< 0.01	Ki67+ cells	0.37	0.06
Total cells	0.88	< 0.0001	Total cells	− 0.35	0.08
Media			Media
Ki67+ cells	− 0.39	0.05	Ki67+ cells	0.00	0.98
Total cells	− 0.39	0.05	Total cells	0.69	< 0.0001

r indicates Pearson’s correlation coefficient; Combined, 63 sections taken from 31 mice; vehicle alone, 20 sections taken from 10 mice; liraglutide alone, 26 sections taken from 11 mice

ISSN: 1475-2840