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Table 1 Clinical characteristics of the study cohort

From: Circulating levels and characterization of microparticles in patients with different degrees of glucose tolerance

 

NGT (n = 53)

PreDM (n = 39)

T2DM (n = 68)

p value

Sex (M/F)

30/23

31/8

42/26

0.124

Age (years)

57 ± 1

60 ± 1

60 ± 1

0.093

BMI (kg/h2)

25 ± 0.4

28 ± 0.6#

30 ± 1.6#

<0.0001

SBP (mmHg)

120 ± 2

143 ± 4#, ¶¶

133 ± 2¶

<0.0001

DBP (mmHg)

78 ± 1

91 ± 2#,##

80 ± 1

<0.0001

HR (bpm)

67 ± 2

74 ± 2¶

74 ± 2¶

0.032

Plasma glucose (mg/dl)

86 ± 1

106 ± 3§,##

160 ± 8#

<0.0001

Total cholesterol (mg/dl)

190 ± 3

198 ± 6

188 ± 5

0.507

HDL cholesterol (mg/dl)

51 ± 2

47 ± 2

50 ± 2

0.155

LDL cholesterol (mg/dl)

121 ± 3

123 ± 5

113 ± 5

0.261

Triglyceride (mg/dl)

113 ± 10

147 ± 9¶

134 ± 13

0.096

  1. Data presented as Mean ± ES (p value ANOVA and Bonferroni test)
  2. NGT glucose normotolerant, PreDM pre-diabetic, T2DM type 2 diabetic mellitus, BMI Body Mass Index, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, bpm beats per minute, HDL high density lipoprotein, LDL low density lipoprotein
  3. #p < 0.0001 vs NGT
  4. §p < 0.01 vs NGT
  5. ¶p < 0.05 vs NGT
  6. ##p < 0.0001 vs T2DM
  7. ¶¶p < 0.05 vs T2DM