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Table 2 Patient demographics and baseline characteristics

From: The use of lipid-lowering therapy and effects of antihyperglycaemic therapy on lipids in subjects with type 2 diabetes with or without cardiovascular disease: a pooled analysis of data from eleven randomized trials with insulin glargine 100 U/mL

Characteristic

Lipid-lowering drug treatment

No lipid-lowering drug treatment

P value

Total (n = 1940)

With CVD (n = 1885)

Total (n = 2828)

With CVD (n = 1787)

Without CVD (n = 1041)

Treated vs non-treated (total populations)

Male,  %

58

58

50

48*

53

<0.001

Age, years

57.9 (9.0)

57.9 (9.0)

55.7 (10.1)

57.1* (9.7)

53.1 (10.4)

<0.001

Weight, kg

89.4 (19.1)

89.6 (19.1)

86.5 (21.2)

88.5* (20.3)

83.3 (22.2)

<0.001

BMI, kg/m2

31.4 (5.4)

31.5 (5.4)

30.9 (6.1)

31.7* (5.8)

29.6 (6.5)

0.004

T2D duration, years

9.1 (6.3)

9.1 (6.3)

8.5 (5.8)

8.7* (5.9)

8.0 (5.5)

<0.001

HbA1c,  %

8.75 (1.03)

8.75 (1.03)

8.89 (1.08)

8.84* (1.06)

8.98 (1.11)

<0.001

FPG, mg/dL

196 (56)

196 (55)

200 (57)

200 (57)

201 (58)

0.01

FPG, mmol/L

10.9 (3.1)

10.9 (3.1)

11.1 (3.2)

11.1 (3.2)

11.2 (3.2)

0.01

Fasting C-peptide, nmol/L

1.18 (0.59)

1.19 (0.60)

1.10 (0.60)

1.15 (0.59)

1.01 (0.60)

<0.001

  1. Data presented represent mean (standard deviation) unless otherwise specified
  2. HbA1c glycosylated haemoglobin, BMI body mass index, CVD cardiovascular disease, T2D type 2 diabetes, FPG fasting plasma glucose
  3. * Statistically significant differences (P < 0.01) between with-CVD and without-CVD groups