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Table 3 Multiple regression analysis of the determinants for aortic PWV

From: Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study

  Model 1 Model 2
β p β p
Age (years) 0.344 <0.001 0.327 <0.001
Sex (male = 1, female = 0) −0.117 0.033 −0.158 0.012
BMI (kg/m2) −0.233 0.001 −0.228 0.007
Systolic blood pressure (mmHg) 0.382 <0.001 0.310 <0.001
Albumin (g/dL) −0.074 0.185 −0.132 0.051
eGFR (mL/min/1.73 m2) −0.113 0.095 −0.150 0.048
Log [HOMA-R]a −0.030 0.692
Log [triglycerides (mg/dL)] −0.092 0.119 −0.105 0.151
HDL-cholesterol (mg/dL) −0.082 0.180 −0.120 0.086
Statins (yes = 1, no = 0) 0.060 0.249 0.101 0.079
RAS inhibitors (yes = 1, no = 0) −0.130 0.025 0.180 0.006
Calcium-channel blockers (yes = 1, no = 0) 0.049 0.412 0.056 0.396
Smokers (yes = 1, no = 0) −0.021 0.698 −0.033 0.606
Log [hs-CRP (mg/L)] 0.024 0.733 0.005 0.950
LBP (μg/mL) 0.135 0.026 0.125 0.083
R 2 0.585 <0.001 0.631 <0.001
  1. β standard regression coefficient determined by multiple regression analysis, R 2 coefficient of determination, PWV pulse wave velocity, BMI body mass index, eGFR estimated glomerular filtration rate, HOMA-R homeostasis model assessment of insulin resistance, HDL high-density lipoprotein, RAS renin-angiotensin system, hs-CRP high-sensitivity C-reactive protein, LBP lipopolysaccharide-binding protein
  2. aSubjects excluding those receiving insulin therapy (n = 144)