Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study

Table 3 Multiple regression analysis of the determinants for aortic PWV

	Model 1		Model 2
	β	p	β	p
Age (years)	0.344	<0.001	0.327	<0.001
Sex (male = 1, female = 0)	−0.117	0.033	−0.158	0.012
BMI (kg/m²)	−0.233	0.001	−0.228	0.007
Systolic blood pressure (mmHg)	0.382	<0.001	0.310	<0.001
Albumin (g/dL)	−0.074	0.185	−0.132	0.051
eGFR (mL/min/1.73 m²)	−0.113	0.095	−0.150	0.048
Log [HOMA-R]^a	–	–	−0.030	0.692
Log [triglycerides (mg/dL)]	−0.092	0.119	−0.105	0.151
HDL-cholesterol (mg/dL)	−0.082	0.180	−0.120	0.086
Statins (yes = 1, no = 0)	0.060	0.249	0.101	0.079
RAS inhibitors (yes = 1, no = 0)	−0.130	0.025	0.180	0.006
Calcium-channel blockers (yes = 1, no = 0)	0.049	0.412	0.056	0.396
Smokers (yes = 1, no = 0)	−0.021	0.698	−0.033	0.606
Log [hs-CRP (mg/L)]	0.024	0.733	0.005	0.950
LBP (μg/mL)	0.135	0.026	0.125	0.083
R ²	0.585	<0.001	0.631	<0.001

β standard regression coefficient determined by multiple regression analysis, R ² coefficient of determination, PWV pulse wave velocity, BMI body mass index, eGFR estimated glomerular filtration rate, HOMA-R homeostasis model assessment of insulin resistance, HDL high-density lipoprotein, RAS renin-angiotensin system, hs-CRP high-sensitivity C-reactive protein, LBP lipopolysaccharide-binding protein
^aSubjects excluding those receiving insulin therapy (n = 144)

ISSN: 1475-2840