Tertiles of LF/TF ratio | ||||||
---|---|---|---|---|---|---|
Lean | Obese | |||||
Lowest tertile (n = 3592) | Second tertile (n = 3590) | Highest tertile (n = 3593) | Lowest tertile (n = 1631) | Second tertile (n = 1627) | Highest tertile (n = 1633) | |
Leg fat (kg) | 4.3 ± 1.4 | 5.1 ± 1.7§ | 5.4 ± 1.8§,∥ | 5.1 ± 1.4 | 6.4 ± 1.7§ | 7.6 ± 2.1§,∥ |
Total fat (kg) | 15.9 ± 4.1 | 15.6 ± 4.4§ | 13.9 ± 4.0§,∥ | 21.5 ± 4.9 | 22.6 ± 5.3§ | 23.0 ± 5.4§ |
LF/TF ratio (%) | 26.4 ± 3.2 | 32.5 ± 3.3§ | 38.7 ± 4.8§,∥ | 23.8 ± 2.2 | 28.1 ± 1.8§ | 33.0 ± 3.2§,∥ |
Age (year) | 57.0 ± 13.5 | 47.5 ± 15.0§ | 38.2 ± 14.2§,∥ | 55.7 ± 12.3 | 51.1 ± 13.9§ | 43.6 ± 14.6§,∥ |
Men (%) | 40.4 | 40.3 | 40.3 | 49.2 | 49.2 | 49.2 |
Waist circumference (cm) | 80.4 ± 6.5 | 76.7 ± 6.9§ | 72.5 ± 7.1§,∥ | 92.0 ± 6.8 | 91.0 ± 7.0§ | 88.6 ± 7.3§,∥ |
BMI (kg/m2) | 22.7 ± 1.7 | 22.0 ± 1.9§ | 20.9 ± 2.1§,∥ | 27.4 ± 2.1 | 27.5 ± 2.3 | 27.2 ± 2.2∥ |
Systolic blood pressure (mmHg) | 122.1 ± 17.9 | 114.0 ± 16.6§ | 107.8 ± 13.6§,∥ | 125.9 ± 16.3 | 122.8 ± 16.4§ | 117.4 ± 15.4§,∥ |
Diastolic blood pressure (mmHg) | 76.2 ± 10.4 | 73.1 ± 10.2§ | 70.1 ± 9.3§,∥ | 79.9 ± 10.2 | 78.9 ± 10.4§ | 76.5 ± 10.2§,∥ |
Fasting plasma glucose (mg/dL) | 102.1 ± 26.6 | 93.6 ± 19.3§ | 89.3 ± 12.2§,∥ | 111.0 ± 31.8 | 101.6 ± 21.0§ | 95.2 ± 15.9§,∥ |
Total cholesterol (mg/dL)a | 194.4 ± 36.6 | 185.2 ± 33.2§ | 172.9 ± 30.0§,∥ | 200.3 ± 37.4 | 198.3 ± 36.5 | 191.3 ± 35.3§,∥ |
HDL cholesterol (mg/dL)a | 50.7 ± 12.0 | 54.6 ± 13.0§ | 57.5 ± 12.6§,∥ | 47.3 ± 10.8 | 47.7 ± 11.1 | 49.8 ± 11.0§,∥ |
Triglycerides (mg/dL)a | 154.4 ± 114.1 | 115.6 ± 87.4§ | 85.1 ± 67.8§,∥ | 190.6 ± 150.1 | 174.0 ± 121.3§ | 136.3 ± 98.3§,∥ |
LDL cholesterol (mg/dL)a | 118.4 ± 33.5 | 112.5 ± 29.5§ | 102.8 ± 26.6§,∥ | 122.1 ± 34.0 | 122.0 ± 32.5 | 119.6 ± 31.3 |
eGFR (mL/min/1.73 m2) | 90.1 ± 16.1 | 97.3 ± 16.5§ | 103.6 ± 16.1§,∥ | 98.1 ± 16.8 | 92.2 ± 16.2§ | 97.9 ± 16.6§,∥ |
WBC (103/μL) | 6.1 ± 1.7 | 5.8 ± 1.6§ | 5.6 ± 1.5§,∥ | 6.6 ± 1.8 | 6.5 ± 1.7 | 6.2 ± 1.6§,∥ |
Insulin (ųU/mL)a | 9.4 ± 5.4 | 8.7 ± 3.9§ | 8.4 ± 3.4§,∥ | 13.0 ± 7.6 | 12.1 ± 5.8 | 11.1 ± 4.6 |
HOMA-IRa | 2.4 ± 2.3 | 2.0 ± 1.1§ | 1.9 ± 0.8§,∥ | 3.7 ± 3.4 | 3.1 ± 1.9§ | 2.6 ± 1.2§,∥ |
Alcohol (g/week) | 73.8 ± 122.5 | 63.5 ± 113.3§ | 44.6 ± 84.2§,∥ | 82.0 ± 132.0 | 78.9 ± 123.5 | 67.8 ± 113.4§ |
Current smoker (%) | 20.5 | 21.6 | 20.9 | 21.3 | 23.3 | 24.2 |
Regular exercise (%)b | 24.2 | 24.7 | 22.0§ | 26.4 | 27.2 | 28.5 |
Hypertension (%) | 37.5 | 17.9§ | 7.0§,∥ | 53.8 | 40.7§ | 24.0§,∥ |
Diabetes (%) | 15.2 | 4.1§ | 1.1§,∥ | 26.4 | 12.2§ | 4.3§,∥ |
Metabolic syndrome (%) | 37.6 | 11.9§ | 2.4§,∥ | 72.4 | 60.2§ | 35.0§,∥ |
Chronic kidney disease (%)c | 4.3 | 2.1§ | 0.6§,∥ | 5.3 | 3.7 | 2.2§ |