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Table 3 Results of stepwise multiple linear regression analyses

From: Subclinical inflammation associated with prolonged TIMP-1 upregulation and arterial stiffness after gestational diabetes mellitus: a hospital-based cohort study

Parameters Covariates included in the model R2 for model Global p Standardized β p value
hsCRP   0.096 <0.001   
BMI    0.259 <0.001
MMP-8   0.138 <0.001   
hsCRP    0.312 <0.001
Previous GDM    −0.137 0.025
TC    0.129 0.036
TIMP-1   0.067 0.003   
Previous GDM    0.157 0.015
BMI    0.149 0.025
Heart rate    −0.132 0.044
C1   0.524 <0.001   
Systolic BP    −0.602 <0.001
Heart rate    −0.347 <0.001
BMI    0.232 <0.001
Time after the index pregnancy    −0.095 0.041
C2   0.317 <0.001   
Systolic BP    −0.345 <0.001
Heart rate    −0.312 <0.001
BMI    0.286 <0.001
Age    −0.191 0.001
Pack-years of smoking    −0.144 0.012
PWV   0.470 <0.001   
Systolic BP    0.534 <0.001
Age    0.230 <0.001
F-Insu    0.191 <0.001
Previous GDM    0.105 0.026
Time after the index pregnancy    −0.102 0.040
  1. Covariates in these analyses included age, BMI, previous GDM, pack-years of smoking, time after the index pregnancy, heart rate, systolic blood pressure, hsCRP, TC and fasting insulin. Final models include significant covariates only. Standardized β provides a measure of the relative strength of an association, independent of the measurement units. Standardized β and p values are shown only when p < 0.05
  2. BMI body mass index, BP blood pressure, F-Insu fasting insulin, GDM gestational diabetes mellitus, hsCRP high-sensitivity C reactive protein, C1 large artery compliance index, C2 small artery compliance index, PWV pulse wave velocity, MMP-8 matrix metalloproteinase-8