Skip to main content

Table 3 Unadjusted and adjusted effects of PAPP-A

From: Pregnancy-associated plasma protein-A is a stronger predictor for adverse cardiovascular outcomes after acute coronary syndrome in type-2 diabetes mellitus

 

All (n = 320)

T2DM (−) (n = 184)

T2DM (+) (n = 136)

HR (95% CI)*

% Δ** (%)

HR (95% CI)*

% Δ** (%)

HR (95% CI)*

%Δ** (%)

Unadjusted

3.10 (2.48–3.87)

0

3.16 (2.27–4.39)

0

2.97 (2.11–4.18)

0

Adjusted for

 Age

2.93 (2.34–3.66)

−5

3.04 (2.14–4.32)

−4

3.16 (2.21–4.53)

6

 Sex

3.05 (2.44–3.82)

−1

3.36 (2.36–4.79)

7

3.04 (2.14–4.31)

2

 LVEF (%)

3.02 (2.41–3.79)

−3

2.96 (2.11–4.17)

−6

2.97 (2.11–4.19)

0

 HbA1C

3.06 (2.43–3.86)

−1

3.18 (2.23–4.55)

1

2.98 (2.11–4.19)

0

 Troponin I

3.09 (2.46–3.88)

0

3.18 (2.27–4.45)

1

2.89 (2.05–4.07)

−3

 hsCRP

2.86 (2.21–3.69)

−8

2.95 (2.02–4.30)

−7

2.79 (1.88–4.13)

−6

  1. HR for 1 SD increase in log10 PAPP-A for single covariates. All adjusted HRs for PAPP-A are adjusted for the single variable that is specified
  2. * p < 0.001 for all variables
  3. ** Percent change in HR compared to the unadjusted HR