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Table 3 Left ventricular function determined by cine MRI in control rats and hyaluronidase-treated rats

From: Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats

 

Control

Hyaluronidase

Baseline

N = 5

Adenosine

Baseline

N = 6

Adenosine

Heart rate (bpm)

384 ± 17

327 ± 21†

425 ± 24

334 ± 19†

EDV (µl)

316 ± 33

348 ± 30

232 ± 21

273 ± 38

ESV (µl)

83 ± 18

55 ± 8

64 ± 6

74 ± 13

SV (µl)

233 ± 42

294 ± 27

168 ± 17

199 ± 44

EF (%)

72 ± 5

84 ± 2

72 ± 2

71 ± 6

  1. Data are expressed as mean ± SEM
  2. EDV end-diastolic volume, SV stroke volume, EF ejection fraction
  3. * p < 0.05 vs. control group, † p < 0.05 adenosine effect. No significant differences were found for the intervention group hyaluronidase compared to the control group
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Cardiovascular Diabetology

ISSN: 1475-2840