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Table 3 Left ventricular function determined by cine MRI in control rats and hyaluronidase-treated rats

From: Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats

  Control Hyaluronidase
Baseline
N = 5
Adenosine Baseline
N = 6
Adenosine
Heart rate (bpm) 384 ± 17 327 ± 21 425 ± 24 334 ± 19
EDV (µl) 316 ± 33 348 ± 30 232 ± 21 273 ± 38
ESV (µl) 83 ± 18 55 ± 8 64 ± 6 74 ± 13
SV (µl) 233 ± 42 294 ± 27 168 ± 17 199 ± 44
EF (%) 72 ± 5 84 ± 2 72 ± 2 71 ± 6
  1. Data are expressed as mean ± SEM
  2. EDV end-diastolic volume, SV stroke volume, EF ejection fraction
  3. * p < 0.05 vs. control group,  p < 0.05 adenosine effect. No significant differences were found for the intervention group hyaluronidase compared to the control group