Table 1 Basic clinical data

Basic clinical data

 n

58

71

41

74

42

67

 Age (years)

48 ± 2.0

54 ± 1.6

68 ± 1.9^ǂǂǂ

68 ± 1.0^ǂǂǂ

60 ± 1.9^ǂǂǂ

65 ± 1.2^ǂǂǂ

 Female  %

59

52

40

43

53

48

 BMI (kg/m²)

34 ± 0.77

37 ± .74

26 ± .40^ǂǂǂ

26 ± 0.47^ǂǂǂ

36 ± .71^×××

36 ± 0.74^×××

 Height (cm)

166 ± 1.4

167 ± 1.1

171 ± 1.7

170 ± 1.2

166 ± 1.9

170 ± 1.4

 Heart rate (bpm)

74 ± 1.7

73 ± 1.7

71 ± 2.4

71 ± 2.0

76 ± 2.6

72 ± 1.8

 Systolic BP (mmHg)

127 ± 1.6

159 ± 3.0***

128 ± 1.6

164 ± 2.0***

128 ± 1.6

161 ± 2.0***

 Diastolic BP (mmHg)

78 ± 1.1

93 ± .77***

75 ± 1.2

95 ± .52***

76 ± 1.5

94 ± 1.5***

 PP (mmHg)

49 ± 1.4

66 ± 2.8***

52 ± 1.7

69 ± 1.9***

53 ± 2.5

68 ± 2.2***

 Glucose (mmol/l)

5.2 ± .10

5.2 ± 0.14

8.4 ± 0.49^ǂǂǂ

8.5 ± 0.51^ǂǂǂ

11 ± 0.72^ǂǂǂ

9.1 ± 0.43^ǂǂǂ

 Cholesterol (mmol/l)

5.1 ± .24

4.7 ± 0.24

4.1 ± 0.3

4.0 ± 0.16

4.1 ± .22

3.9 ± 0.11

 HDL-C (mmol/l)

1.3 ± .07

1.5 ± 0.13

1.2 ± 0.09

1.2 ± .04

1.2 ± 0.12

1.2 ± 0.05

 LDL-C (mmol/l)

3.1 ± .23

2.6 ± 0.28

2.2 ± 0.21^ǂ

1.9 ± 0.11^ǂ

1.9 ± 0.16^ǂ

1.8 ± 0.10^ǂ

 Triglycerides (mmol/l)

1.9 ± 1.3

1.6 ± 0.13

2.0 ± 0.34

1.9 ± 0.16

2.4 ± 0.33

2.4 ± 0.20

History anti-hyperglycaemic and anti-hypertensive medication (%)

 Biguanides

8.62

1.41

26.83^ǂǂ

47.30^ǂǂ

47.30^ǂǂǂ

50.72^ǂǂ

 DPP-4 inhibitors

0

0

4.88^ǂǂ

6.76^ǂǂ

0%

7.46^ǂǂ

 Sulphonylureas

0

0

17.07^ǂǂ

41.89^ǂǂ

33.33^ǂǂ

41.79^ǂǂ

 Insulin

0

0

24.39^ǂǂ

16.22^ǂǂ

40.48^ǂǂ

25.37^ǂǂ

 ACE inhibitors

0

16.90***

0

33.78***

0

46.27***

 Ang II antagonists

0

15.14***

0

20.27***

0

19.40***

 Beta-blockers

0

18.31***

0

49.32***

0

58.21***

 Ca²+ channel blockers

0

11.27***

0

14.86***

0

11.94***