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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Inhibition of dynamin-related protein 1 protects against myocardial ischemia–reperfusion injury in diabetic mice

Fig. 6

Mdivi-1 suppressed myocardial apoptosis following myocardial ischemia/reperfusion (MI/R) in diabetic mice. a Top representative terminal deoxynucleotidyl nick-end labeling (TUNEL)-stained and 4’,6-diamino-2-phenylindole (DAPI)-stained photomicrographs. Original magnification ×400. Bottom percentage of apoptotic cells (green fluorescence)/the total number of nucleated cells (blue fluorescence). b Myocardial caspase-3 activity (fold over Sham). MI/R group means diabetic mice subjected to MI/R and vehicle (dimethyl sulfoxide) administration. Values are mean ± SEM. N = 8 hearts for each group. **P < 0.01 vs. Sham. ## P < 0.01 vs. MI/R

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Cardiovascular Diabetology

ISSN: 1475-2840