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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Inhibition of dynamin-related protein 1 protects against myocardial ischemia–reperfusion injury in diabetic mice

Fig. 4

Mdivi-1 improved cardiac function in diabetic mice subjected to MI/R. a Representative echocardiography images. b Left ventricular ejection fraction (LVEF). c Left ventricular end-systolic volume (LVESV). d Left ventricular end-diastolic volume (LVEDV). (E and F) ± LV dp/dt max, the instantaneous first derivation of left ventricle pressure. MI/R group means diabetic mice subjected to MI/R and vehicle (dimethyl sulfoxide) administration. Values are mean ± SEM. N = 8 animals for each group. **P < 0.01 vs. Sham. # P < 0.05, ## P < 0.01 vs. MI/R

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