Fig. 1

Effect of short-term (7 days) empagliflozin treatment on various parameters (a–f) obtained from daily metabolic cage analysis of SHRcp. Control SHRcp fed control diet; SGLT2, SHRcp fed control diet containing empagliflozin; UGE urinary glucose excretion; NS not significant. Values are mean ± SEM n = 6 in control, n = 5 in SGLT2. Statistical analysis was performed by two-factor ANOVA with repeated measures followed by post hoc Bonferroni’s multiple comparisons test. ^#P < 0.05, *P < 0.01 versus control