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Table 1 COMBINE OCT–FFR inclusion and exclusion criteria

From: Combined optical coherence tomography morphologic and fractional flow reserve hemodynamic assessment of non- culprit lesions to better predict adverse event outcomes in diabetes mellitus patients: COMBINE (OCT–FFR) prospective study. Rationale and design

Inclusion criteria

 Age ≥18 years

 History of DM with any indication for angiography (Stable Angina Pectoris or any type of ACS)

 At least ≥ 1 de novo target lesion in a native coronary segment with a visually estimated diameter stenosis of between ≥40 and ≤80 %

Exclusion criteria

 TIMI flow <3 in the target lesion(s)

 Target lesion reference diameter <2.0 mm

 Left Ventricular ejection fraction <30 %

 Malignancy

 Life expectancy <2 years

 Unwilling or unable to provide informed consent

  1. DM denotes diabetes mellitus; ACS denotes acute coronary syndrome; TIMI denotes thrombolysis in myocardial infarction