Serum bicarbonate quintile (mmol/L) | ||||||
---|---|---|---|---|---|---|
Q1 ≤23 | Q2 24–25 | Q3 26–27 | Q4 28 | Q5 ≥29 | All increase of 1 | |
All-cause mortality | ||||||
Number | 183 | 219 | 341 | 178 | 362 | 1283a |
Number of events (%) | 104 (56.8) | 122 (55.7) | 182 (53.4) | 97 (54.5) | 227 (62.7) | 732 (57.1) |
Unadjusted | 1.27 (1.004–1.60) | 1.07 (0.86–1.33) | 1.02 (0.84–1.24) | 1.01 (0.80–1.29) | 1.00 (reference) | 0.98 (0.96–1.004) |
Adjustedb | 1.25 (0.96–1.63) | 1.07 (0.83–1.38) | 1.04 (0.83–1.29) | 1.10 (0.84–1.43) | 1.00 (reference) | 0.98 (0.95–1.004) |
Coronary heart disease | ||||||
Number | 135 | 154 | 248 | 138 | 230 | 905c |
Number of events (%) | 59 (43.7) | 70 (45.5) | 93 (37.5) | 50 (36.2) | 89 (38.7) | 361 (39.9) |
Unadjusted | 1.58 (1.14–2.20) | 1.53 (1.12–2.10) | 1.14 (0.86–1.53) | 0.97 (0.68–1.37) | 1.00 (reference) | 0.94 (0.91–0.97) |
Adjustedd | 1.39 (0.97–1.98) | 1.23 (0.88–1.72) | 0.97 (0.71–1.31) | 0.92 (0.64–1.32) | 1.00 (reference) | 0.95 (0.92–0.99) |
Heart failure | ||||||
Number | 172 | 200 | 325 | 167 | 310 | 1174e |
Number of events (%) | 66 (38.4) | 58 (29.0) | 98 (30.2) | 44 (26.3) | 108 (34.8) | 374 (31.9) |
Unadjusted | 1.54 (1.13–2.09) | 1.04 (0.76–1.43) | 1.05 (0.80–1.38) | 0.81 (0.57–1.15) | 1.00 (reference) | 0.95 (0.92–0.98) |
Adjustedf | 1.08 (0.76–1.53) | 0.82 (0.58–1.16) | 0.90 (0.67–1.21) | 0.77 (0.52–1.13) | 1.00 (reference) | 0.99 (0.95–1.03) |