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Table 1 General characteristics of experimental group

From: N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats

 

C

D

D + NAC

Plasma glucose (mM)

6.41 ± 0.61

29.12 ± 5.13**

25.86 ± 2.76**

Heart weight (g)

1.62 ± 0.23

1.21 ± 0.17*

1.38 ± 0.20*

Body weight (g)

450.5 ± 20.3

263.7 ± 17.6*

362.5 ± 24.2*#

Heart weight/bodyweight (mg/g)

3.59 ± 0.09

4.58 ± 0.12*

3.81 ± 0.11#

  1. Control (C) or STZ-induced diabetic (D) rats were either untreated or treated with N-acetylcysteine (1.5 g/kg/day, D + NAC) by oral gavage for 4 weeks. All the results are expressed as mean ± SD, n = 8. Differences in general characteristics among the three groups were determined by using one-way ANOVA followed by Tukey’s test
  2. * P < 0.05
  3. ** P < 0.01 vs. C group
  4. # P < 0.05 vs. D group
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Cardiovascular Diabetology

ISSN: 1475-2840