Fig. 1
From: Current perspectives on cardiovascular outcome trials in diabetes
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12933-016-0456-8/MediaObjects/12933_2016_456_Fig1_HTML.jpg)
Confidence interval (CI) bars indicated by FDA guideline. Shown are five examples of hazard ratios (HR) and the upper limit of the 95Â % CI of a development plan and regulatory consequences of each outcome. S superiority, NI non-inferiority, I inferiority, UP underpowered