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Table 1 Baseline characteristics of study population by categories of PRAL

From: Association between dietary acid load and the risk of cardiovascular disease: nationwide surveys (KNHANES 2008–2011)

 

Tertiles of dietary PRAL (mEq/day)

P value*

T1 (n = 3859)

T2 (n = 3540)

T3 (n = 4202)

PRAL (mEq/d)a

−21.8 (−199.8 ~ −7.5)

−2.9 (−11.3 ~ 8.2)

11.2 (−10.4 ~ 181.4)

<0.001

DAL (mEq/d)

11.1 ± 20.8

35.9 ± 6.5

53.4 ± 14.6

<0.001

Magnesium (mg/d)

388.0 ± 186.4

278.1 ± 139.4

307.8 ± 177.2

<0.001

Age (year)

56.2 ± 10.3

57.1 ± 11.0

56.8 ± 11.2

0.001

Male (%)

41.4

41.3

41.8

0.881

Waist circumference (cm)

82.7 ± 9.0

82.5 ± 9.2

82.9 ± 9.3

0.255

BMI (kg/m2)

24.1 ± 3.0

23.9 ± 3.1

24.0 ± 3.1

0.041

Systolic blood pressure (mmHg)

120.4 ± 17.2

122.1 ± 18.0

122.2 ± 17.6

<0.001

Diastolic blood pressure (mmHg)

76.3 ± 10.1

76.8 ± 10.6

77.2 ± 10.5

0.001

Fasting plasma glucose (mg/dL)

101.4 ± 27.5

100.5 ± 23.3

100.6 ± 24.9

0.213

Total cholesterol (mg/dL)b

193.2 ± 36.1

194.1 ± 36.7

194.3 ± 36.5

0.436

HDL cholesterol (mg/dL)b

51.1 ± 12.3

51.1 ± 12.6

51.2 ± 12.5

0.842

Triglycerides (mg/dL)b

138.8 ± 102.7

145.5 ± 119.8

144.7 ± 113.5

0.004

LDL cholesterol (mg/dL)b

119.0 ± 32.4

119.2 ± 32.6

119.0 ± 32.3

0.043

Creatinine (mg/dL)

0.8 ± 0.2

0.8 ± 0.2

0.8 ± 0.3

0.903

eGFR (mL/min/1.73 m2)

88.3 ± 14.9

87.9 ± 15.0

88.5 ± 15.5

0.193

Insulin (ųU/mL)b

9.8 ± 5.2

9.8 ± 5.9

10.0 ± 6.5

0.807

HOMA-IRb

2.5 ± 1.9

2.5 ± 1.8

2.5 ± 2.5

0.962

Urine pH

5.8 ± 0.9

5.7 ± 0.9

5.7 ± 0.8

0.013

Heavy drink (%)

12.3

14.1

17.0

<0.001

Current smoking (%)

15.4

17.8

20.0

<0.001

Exercise (%)

28.3

24.6

24.6

<0.001

Hypertension (%)

34.4

37.9

38.5

<0.001

IFG/Diabetes (%)

23.3/13.4

24.2/13.4

25.0/12.7

0.427

Metabolic syndrome (%)

37.1

38.8

40.2

0.014

Chronic kidney disease (%)

3.8

4.3

4.5

0.263

Region (Metro/City/Rural,  %)

43.3/30.2/26.5

42.3/31.5/26.3

41.7/30.2/28.1

0.237

Family history of cardio- or cerebro-vascular disease (%)

6.6

6.3

6.7

0.811

  1. PRAL potential renal acid load; DAL dietary acid load; BMI body mass index; HDL cholesterol, high density lipoprotein cholesterol; LDL cholesterol, low density lipoprotein cholesterol; eGFR estimated glomerular filtration rate; HOMA-IR homeostasis model assessment of insulin resistance; IFG impaired fasting glucose
  2. P < 0.05 by post hoc analyses when compared with lowest tertiles
  3. *Chi square tests for qualitative variables and ANOVA tests for quantitative variables
  4. aValues are medians per tertile
  5. bLog-transformed