Fig. 1

Impaired antioxidant response profiles in HUVECs during high and oscillating glucose exposure. SOD-1, SOD-2, CAT and GPx-1 in OG, HG and NG: a mRNA q-PCR real time, b densitometry analyses c one representative western blot, d activity of GPx. Data are expressed as mean (±SEM). *p < 0.05, **p < 0.01, ***p < 0.001 vs control. Symbols over the bars refer to differences between the conditions shown under the bars (^§p < 0.05, ^§§p < 0.01, ^§§§p < 0.001)