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Table 2 Mean values of the serum insulin level in CON, CON +100 mg/kg/day berberine, diabetic, and diabetic +100 mg/kg/day berberine rats at 8 weeks after STZ-injection in Experiment I

From: Berberine alleviates the cerebrovascular contractility in streptozotocin-induced diabetic rats through modulation of intracellular Ca2+ handling in smooth muscle cells

Group

Insulin (μIU/ml)

CON (n = 20)

9.0 ± 1.5

CON + berberine (n = 20)

8.7 ± 1.7

Diabetic (n = 20)

13.6 ± 1.8*

Diabetic + berberine (n = 20)

11.5 ± 1.2#,*

  1. CON control rats, CON + berberine control rats administrated with berberine (100 mg/kg/day), Diabetic diabetic rats, diabetic + berberine diabetic rats administrated with berberine (100 mg/kg/day). * P < 0.05 vs. CON and # P < 0.05 vs. diabetic rats