Fig. 2
From: Nicorandil attenuates carotid intimal hyperplasia after balloon catheter injury in diabetic rats
Intimal hyperplasia 14 days after balloon injury. a Cross sections of carotid arteries from diabetic rats 14 days after balloon injury. Sections were stained with Elastica van Gieson. b Quantitative analysis of intima area. c Quantitative analysis of intima/media area ratio. d Quantitative analysis of lumen area. e Quantitative analysis of media area in DM-sham group, DM-injury group, DM-injury + nicorandil group, and DM-injury + nicorandil + 5HD group. Nicorandil reduced the intima area and intima/media ratio, and it increased lumen area. The protective effect of nicorandil was significantly blocked by 5-HD. No significant difference was seen in media areas of different groups. Bars represent mean ± SE. **p < 0.01, *p < 0.05