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Table 1 Baseline and demographic parameters

From: Determinants of growth differentiation factor 15 in patients with stable and acute coronary artery disease. A prospective observational study

Variable

SCAD (n = 189)

STEMI (n = 121)

NSTEMI (n = 163)

P value

Age

65.2 ± 0.786

61.9 ± 1.34

64.9 ± 1.05

0.067

Age >75 (%)

41 (21.7)

29 (24)

45 (27.6)

0.433

Female gender (%)

55 (29.1)

41 (33.9)

54 (33.1)

0.60

Hypertension (%)

170 (90)

98 (81)

139 (85.3)

0.058

Hyperlipidemia (%)

160 (85.1)

83 (68.6)

129 (79.1)

0.002

Current smoking (%)

39 (20.6)

44 (36.4)

52 (31.9)

0.006

DM (%)

58 (30.9)

28 (23.1)

50 (30.7)

0.27

Family history of CAD (%)

77 (41)

45 (37.2)

62 (38)

0.766

Previous MI (%)

63 (33.5)

19 (15.7)

42 (25.8)

0.002

CKD (%)

33 (17.5)

19 (15.7)

30 (18.4)

0.83

GDF-15 pg/ml

1421.1 ± 74.9

2189.2 ± 206.7

1695 ± 114.8

<0.0001

BMI (Kg/m2)

28.51 ± 0.35

28 ± 0.43

27.97 ± 0.35

0.499

e-GFR (ml/min)

65.27 ± 0.71

63.65 ± 1.04

63.57 ± 1.03

0.31

CRP (mg/dl)

7.83 ± 2.28

17.42 ± 3.88

11.05 ± 2.26

0.062

Cholesterol (mg/dl)

178.5 ± 3.66

184.25 ± 3.89

182.73 ± 4.16

0.56

HDL-cholesterol (mg/dl)

46.04 ± 1.11

41.01 ± 1.17

43.42 ± 1.13

0.009

LDL-cholesterol (mg/dl)

102.34 ± 2.88

113.58 ± 3.63

109.88 ± 3.44

0.051

Triglycerides (mg/dl)

148.73 ± 7.29

143.17 ± 10.81

163.78 ± 12.52

0.38

Systolic blood pressure (mmHg)

137.8 ± 1.5

139.4 ± 2.5

144.2 ± 2.4

0.070

Diastolic blood pressure (mmHg)

80.1 ± 0.91

81.9 ± 1.7

81.6 ± 1.3

0.507

Hospitalization days

4.84 ± 0.31

12.94 ± 1.22

7.32 ± 0.58

<0.0001

  1. DM diabetes mellitus, CAD coronary artery disease, CKD chronic kidney disease, GDF-15 growth differentiation factor 15, BMI body mass index, e-GFR estimated glomerular filtration rate, CRP high sensitive C-reactive protein, HDL high-density lipoprotein, LDL low-density lipoprotein