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Table 3 Changes in electrocardiography and echocardiography parameters

From: Cardiovascular efficacy of sitagliptin in patients with diabetes at high risk of cardiovascular disease: a 12-month follow-up

 

Baseline

12 months

P value

Electrocardiography parameters

 HR (bpm)

61.2 ± 10.5

65.0 ± 11.9

<0.0001

 Sinus rhythm (%)

90.1

89.0

 

 PR interval (ms)

179.5 ± 32.2

180.5 ± 31.4

0.5784

 QRS interval (ms)

98.0 ± 19.1

97.9 ± 18.2

0.7720

 SV1 + RV5 voltage (mm)

2.7 ± 0.8

2.6 ± 0.7

0.1288

 QT interval (ms)

427.9 ± 34.0

417.9 ± 34.5

0.0004

 QTc interval (ms)

428.1 ± 22.6

425.2 ± 21.9

0.0933

Echocardiography parameters

 LV Dd (mm)

49.9 ± 6.3

49.5 ± 6.3

0.0803

 LV Ds (mm)

33.2 ± 8.2

32.7 ± 7.9

0.0720

 IVST (mm)

8.9 ± 1.9

8.9 ± 1.8

0.7381

 PWT (mm)

9.3 ± 6.0

9.3 ± 6.0

0.6180

 EF (%)

59.7 ± 12.3

60.0 ± 11.8

0.4006

 LV mass index (g/m2)

109.9 ± 33.5

105.1 ± 31.9

0.0270

 E-wave velocity (m/s)

68.2 ± 19.5

68.4 ± 20.0

0.7217

 A-wave velocity (m/s)

78.6 ± 21.8

80.7 ± 20.8

0.3428

 Dct (ms)

216.9 ± 58.5

223.9 ± 54.8

0.3279

 E/A ratio

0.91 ± 0.45

0.85 ± 0.31

0.2005

 e′ (cm/s)

6.08 ± 2.06

5.87 ± 1.59

0.0938

 E/e′ ratio

12.11 ± 5.20

12.34 ± 5.22

0.4858

  1. Values are the mean ± SD or %
  2. Dct deceleration time, Dd dimension of diastole, Ds dimension of systole, EF ejection fraction, HR heart rate, IVST interventricular septal thickness, LV left ventricular PWT posterior wall thickness