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Fig. 7 | Cardiovascular Diabetology

Fig. 7

From: Protective effect of resveratrol and quercetin on in vitro-induced diabetic mouse corpus cavernosum

Fig. 7

Effect of quercetin on high glucose and methylglyoxal-induced deficits in mesenteric artery and corpora cavernosa. Acetylcholine (Ach)-induced relaxations of a mesenteric artery and b corpora cavernosa after 2 h incubation with high glucose (HG, 30 mM) and methylglyoxal (MGO, 120 µM) in absence and presence of quercetin (Quer, 3 µM for a; 30 µM for b) after precontraction with Phe (10 µM for mesenteric arteries; 5 µM for corpora cavernosa). c Electrical field stimulated (EFS) relaxations of 5 µM Phe-precontracted mouse corpora cavernosa after 2 h incubation with high glucose (HG, 30 mM) and methylglyoxal (MGO, 120 µM) in absence and presence of quercetin (Quer, 30 µM). Data are expressed as % decrease of Phe-induced tone; Mann–Whitney U test; #p < 0.01 and *p < 0.05 (n = 4–7)

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