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Table 1 Baseline demographic data and clinical characteristics of the study population

From: Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus

Variable

HPR (n = 233)

Non-HPR (n = 441)

p

Age, y

61.7 ± 9.3

62.0 ± 9.1

0.65

Males, n (%)

141 (60.5)

287 (65.1)

0.27

Smoking, n (%)

104 (44.6)

204 (46.3)

0.69

Hypertension, n (%)

169 (72.5)

292 (66.2)

0.09

BMI (kg/m2)

26.1 ± 3.4

25.9 ± 4.0

0.62

Triglycerides (mmol/L)

2.4 ± 1.8

2.3 ± 1.8

0.23

Total cholesterol (mmol/L)

4.2 ± 1.3

4.1 ± 1.1

0.12

LDL-C (mmol/L)

2.3 ± 0.9

2.2 ± 0.8

0.53

HDL-C (mmol/L)

1.1 ± 0.4

1.2 ± 0.4

0.85

HbA1C (%)

7.3 ± 1.1

7.4 ± 1.3

0.59

Hyperlipidemia, n (%)

127 (54.5)

223 (50.6)

0.33

Insulin-treated diabetes, n (%)

61 (26.2)

97 (22.0)

0.22

Previous MI, n (%)

48 (20.6)

102 (23.1)

0.45

Previous stroke, n (%)

27 (11.6)

36 (8.2)

0.15

Chronic renal dysfunction, n (%)

23 (9.9)

52 (11.8)

0.52

Essential medicine, n (%)

 ACEI/ARB

152 (62.5)

255 (57.8)

0.06

 β-blocker

139 (59.7)

275 (62.4)

0.50

 Calcium channel blocker

57 (24.5)

123 (27.9)

0.34

 Statins

211 (90.6)

394 (89.3)

0.62

 Nitrates

110 (47.2)

193 (43.8)

0.39

  1. Data are expressed as mean ± SD, or n (%)
  2. BMI body mass index; LDL-C low density lipoprotein cholesterol; HDL-C high density lipoprotein cholesterol; HbA1C hemoglobin A1C; MI myocardial infarction; ACEI angiotensin converting enzyme inhibitors; ARB angiotensin II receptor blockers