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Table 2 Associations between carotid, lower-limb atherosclerosis and CVEs, CBVEs, CCBVEs

From: The coexistence of carotid and lower extremity atherosclerosis further increases cardio-cerebrovascular risk in type 2 diabetes

 

ORs (95 % CI)

p value for trend

Without AS

With either carotid or lower limb AS

With both carotid and lower limb AS

CVEs

 Model I

1 (ref)

6.405 (1.484–27.651)

13.841 (3.322–57.677)

<0.001

 Model II

1 (ref)

6.090 (1.405–26.399)

13.302 (3.183–55.589)

<0.001

 Model III

1 (ref)

4.742 (1.050–21.411)

11.306 (2.602–49.129)

<0.001

CBVEs

 Model I

1 (ref)

1.429 (0.869–2.350)

2.218 (1.351–3.642)

0.001

 Model II

1 (ref)

1.401 (0.833–2.356)

2.169 (1.290–3.645)

0.002

 Model III

1 (ref)

1.389 (0.780–2.475)

2.092 (1.1710–3.738)

0.011

CCBVEs

 Model I

1 (ref)

1.690 (1.052–2.714)

2.708 (1.681–4.362)

<0.001

 Model II

1 (ref)

1.685 (1.030–2.756)

2.749 (1.675–4.510)

<0.001

 Model III

1 (ref)

1.724 (1.001–2.966)

2.869 (1.660–4.960)

<0.001

  1. Model I: Adjusted for age, sex, smoking, alcohol, DD, MetS, hypertension and CKD
  2. Model II: Adjusted for age, sex, smoking, alcohol, DD, MetS, hypertension, CKD, BMI, WHR, SBP and DBP
  3. Model III: Adjusted for age, sex, smoking, alcohol, DD, MetS, hypertension, CKD, BMI, WHR, SBP, DBP, FPG, 2h PPG, HbA1c, CRP, FCP, 2h C-P, SCr, SUA, TG, TC, HDL-C and LDL-C
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Cardiovascular Diabetology

ISSN: 1475-2840