Fig. 2

Low circulating PTX3 during pregnancy and at 5-year follow-up is associated with increased cardiovascular disease (CVD) risk. a PTX3 and CRP levels at follow-up according the TG/HDL-C ratio representing increased CVD risk (>1.09), LDL/HDL-C ratio >3.0 and apoB/apoA ratio representing low (<0.60), moderate (≥ 0.60–0.79) and high risk (≥0.80) for coronary artery disease (CAD). *p < 0.05, **p < 0. 01, ***p < 0.001 vs. reference group (green); ^††p < 0.01 vs. intermediate risk (≥0.59 <0.79). b Adjusted risk models for PTX3, BMI, systolic BP and CRP at follow-up for moderate and high risk as reflected by apoB/apoA ratio, LDL/HDL-C ratio and the TG/HDL-C ratio according to cut-offs in A. c Univariate (red circles) and adjusted (blue circles) models for moderate and increased CVD risk as reflected by apoB/apoA ratios by PTX3 during pregnancy. d Univariate (red circles) and adjusted (blue circles) models for increased CVD risk as reflected by LDL/HDL-C ratio by PTX3 during pregnancy. e Univariate (red circles) and adjusted (blue circles) models for increased CVD risk as reflected by the TG/HDL-C ratio by PTX3 during pregnancy. The adjusted analysis included BMI and systolic BP acquired at the same time as the PTX3 measurement. PTX3, BMI, systolic BP and CRP are expressed as log change per SD. For PTX3 the inverse function is given to reflect increasing risk with lower levels. *p < 0.05, **p < 0. 01, ***p < 0.001 vs. reference group