Table 1 Characteristics of the study animals
Tracer | Mouse strain | N of mice (m/f) | Weight (g) | Age (months) | High-fat diet (months) | Injected radioactivity (MBq) | ARG (n) |
|---|---|---|---|---|---|---|---|
18F-FMCH | LDLR−/−ApoB100/100 | 11 (7/4) | 33.2 ± 6.0 | 6.5 ± 0.1 | 4.4 ± 0.0 | 9.4 ± 0.9 | 8 |
IGF-II/LDLR−/−ApoB100/100 | 11 (6/5) | 32.4 ± 6.8 | 6.4 ± 0.3 | 3.9 ± 0.5 | 10.3 ± 0.6 | 11 | |
C57BL/6N | 13 (9/4) | 38.2 ± 7.9 | 8.0 ± 2.6 | NA | 11.3 ± 2.2 | 6 | |
PET/CT IGFII/LDLR−/−ApoB100/100 | 3 (0/3) | 25.0 ± 3.1 | 4.6 ± 0.0 | 2.8 ± 0.0 | 5.7 ± 0.5 | 3 | |
18F-FDG | LDLR−/−ApoB100/100 | 12 (8/4) | 35.8 ± 8.8 | 6.6 ± 0.3 | 4.4 ± 0.2 | 11.2 ± 1.8 | 12 |
IGF-II/LDLR−/−ApoB100/100 | 11 (6/5) | 34.7 ± 7.6 | 6.5 ± 0.4 | 4.2 ± 0.3 | 10.8 ± 1.4 | 11 |