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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Evidence of a causal relationship between high serum adiponectin levels and increased cardiovascular mortality rate in patients with type 2 diabetes

Fig. 1

a Instrumental variable analysis for total adiponectin circulating levels. β1 effect size of association between each minor allele of rs822354 and total adiponectin levels; β2 effect size of association between each minor allele of SNP rs822354 and CV mortality; β3 effect size of association between change of total adiponectin levels attributable to the effect of rs822354 (i.e. genetic equivalent of total adiponectin change) and CV mortality. b Instrumental variable analysis for HMW adiponectin circulating levels. β1 effect size of association between each minor allele of rs822354 and HMW adiponectin levels; β2 effect size of association between each minor allele of SNP rs822354 and CV mortality; β3 effect size of association between change of HMW adiponectin levels attributable to the effect of rs822354 (i.e. genetic equivalent of HMW adiponectin change) and CV mortality

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