Interleukin-6 predicts inflammation-induced increase of Glucagon-like peptide-1 in humans in response to cardiac surgery with association to parameters of glucose metabolism

Table 2 Spearman-Coefficient of GLP-1 with different parameters for each time point

Time-point	1	2	3	4	5
IL6	0.114	0.582	0.490	0.498	−0.058
P value	0.6150	0.0045	0.0207	0.0182	0.8260
Cortisol	0.427	0.199	−0.085	0.041	0.519
P value	0.0606	0.3743	0.7074	0.8550	0.0273
C-Peptide	0.360	0.179	0.406	0.440	−0.056
P value	0.1003	0.4252	0.0612	0.0404	0.8239
Insulin	−0.276	0.147	−0.199	−0.163	0.078
P value	0.213	0.5146	0.3744	0.4698	0.7598
Glucose	0.115	0.039	0.168	−0.013	0.040
P value	0.6104	0.8632	0.4558	0.9541	0.8762
Leptin	−0.299	−0.605	−0.543	−0.524	0.286
P value	0.1873	0.0037	0.0109	0.0147	0.2834
Resistin	0.218	0.134	0.187	0.166	0.424
P value	0.3418	0.5622	0.416	0.4716	0.1016
TNFa	0.169	0.088	−0.008	0.059	−0.252
P value	0.4632	0.7050	0.9732	0.7984	0.3640
Adiponectin	−0.021	0.021	−0.282	−0.239	0.121
P value	0.9335	0.9293	0.2160	0.2964	0.6559
Adrenalin-Inf.	−0.021	0.820	0.109	0.178	−0.197
P value	0.9356	<0.0001	0.6676	0.4793	0.4182
Insulin-Inf.	–	0.100	0.064	−0.002	0.498
P value	–	0.6594	0.7757	0.9931	0.0591

No insulin-infusion was present at baseline; time point 1: directly before surgery (baseline), time point 2: at arrival in the intensive care unit (4–6 h time point), time point 3: 6 h post arrival to the ICU (10–12 h time point), time point 4: morning of the first and time point 5: morning of the second postoperative day

ISSN: 1475-2840