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Table 1 Demographic and clinical data of study participants

From: Increased FGF23 serum level is associated with unstable carotid plaque in type 2 diabetic subjects with internal carotid stenosis

 

ICAS

WICAS

P value

(n = 361)

(n = 598)

Men/female, n

125:236

228:370

0.561†

Age (years ± SD)

72.3 ± 4.2

71.9 ± 3.9

0.204*

Diabetes duration, (years ± SD)

13.1 ± 4.2

12.4 ± 3.5

0.247*

BMI (Kg/m2 ± SD)

30.2 ± 6.5

27.6 ± 4.8

<0.01*

Smoking (current), n (%)

125 (34.6)

194 (32.4)

0.145†

Smoking (former), n (%)

163 (45.2)

279 (46.7)

0.112†

Hypertension, n (%)

234 (64.8)

248 (41.5)

<0.01†

CAD, n (%)

201 (55.7)

191 (31.9)

<0.01†

HIS, n (%)

174 (48.2)

0 (0.0)

<0.01†

PAD, n (%)

115 (31.9)

106 (17.7)

<0.01†

Hypercholesterolemia, n (%)

291 (80.6)

161 (26.9)

<0.01†

LDL-C (mg/dL ± SD)

213 ± 29.8

149 ± 21.2

<0.01†

Triglycerides (mg/dL ± SD)

184 ± 21.3

143 ± 18.8

<0.01†

Statins, n (%)

295 (81.7)

165 (27.6 %)

<0.01†

Antihypertensive drugs, n (%)

229 (63.4)

237 (39.6)

<0.01†

Anti-diabetic treatment

 Diet only, n (%)

38 (10.5)

65 (10.9)

0.563†

 Oral Agents, n (%)

178 (49.3)

292 (48.8)

0.428†

 Insulin therapy, n (%)

145 (40.2)

241 (40.3)

0.394†

eGFR (mL/min/1.73 m2 ± SD)

68.8 ± 15.2

91.1 ± 19.8

<0.001

Phosphate (mg/dL ± SD)

3.01 ± 1.32

2.89 ± 1.13

0.234

Calcium, mg/dL

9.3 ± 0.4

9.5 ± 0.6

0.763

  1. BMI body mass index, CAD coronary artery disease, HIS history of ischemic stroke, PAD peripheral artery disease, LDL-C low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate
  2. * Statistical test performed with Student’s t-test
  3. †Chi square test for categorical values