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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats

Fig. 6

SIRT1 overexpression increased eNOS activity and eNOS phosphorylation, and attenuated eNOS acetylation in diabetic heart. a Top representative blot images. Bottom quantitative analysis of eNOS expression; b eNOS activity. c, d Top representative blot images. Bottom quantitative analysis of phosphorylated eNOS (p-eNOS) and acetylated eNOS (Ac-eNOS). NS, non-diabetic sham rats; DS, diabetic sham rats; DIR, diabetic I/R receiving Ad-GFP rats; Ad.SIRT1, diabetic I/R receiving Ad-SIRT1 rats. Values are mean ± SEM. n = 4–6. *P < 0.05 vs. NS; # P < 0.05 vs. DS; τ P < 0.05 vs. DIR

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