Fig. 3
From: SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats
Up-regulation of SIRT1 reduced MI/R injury in diabetic rats. a Serum creatine kinase-MB (CK-MB) levels. b Serum lactate dehydrogenase (LDH) levels. c Representative photos of myocardial infarct size. d Myocardial infarct size expressed as a percent of infarct area (INF) over total area at risk (AAR). NS, non-diabetic sham rats; NIR, non-diabetic I/R rats receiving Ad-GFP; DS, diabetic sham rats; DIR, diabetic I/R rats receiving Ad-GFP; Ad.SIRT1, diabetic I/R rats receiving Ad-SIRT1. Values are mean ± SEM. n = 8. **P < 0.01 vs. NS; ## P < 0.01 vs. NIR; τ P < 0.05 vs. DIR