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Table 3 Changes in target organ damage by gender

From: Gender differences in the progression of target organ damage in patients with increased insulin resistance: the LOD-DIABETES study

  Global Men Women p
n = 112 n = 61 n = 41
Vascular
 C IMT average baseline (mm) 0.775 ± 0.121 0.779 ± 0.127 0.715 ± 0.092 0.003
 C IMT average final (mm) 0.780 ± 0.123 0.796 ± 0.126 0.754 ± 0.115 0.084
 Difference (final–baseline) 0.025 ± 0.077 0.017 ± 0.070 0.039 ± 0.087 0.147
 Annual increase 0.007 ± 0.023 0.005 ± 0.021 0.011 ± 0.025 0.215
 Annual increase in diabetic patients 0.011 ± 0.002 0.007 ± 0.022 0.018 ± 0.027 0.021
 ABI baseline 1.129 ± 0.121 1.116 ± 0.120 1.080 ± 0.109 0.001
 ABI final 1.179 ± 0.107 1.190 ± 0.11 1.160 ± 0.09 0.128
 Difference (final–baseline) 0.049 ± 0.148 0.033 ± 0.155 0.076 ± 0.135 0.142
 Annual increase 0.015 ± 0.044 0.010 ± 0.045 0.022 ± 0.021 0.157
 Annual increase in diabetic patients 0.011 ± 0.042 0.004 ± 0.671 0.021 ± 0.512 0.157
 PWV baseline (m/sec) 9.470 ± 2.467 9.310 ± 2.324 9.740 ± 2.695 0.393
 PWV final (m/sec) 9.594 ± 2.643 9.476 ± 2.472 9.788 ± 2.922 0.507
 Difference (final–baseline) 0.108 ± 2.255 0.146 ± 2.029 0.046 ± 2.603 0.551
 Annual increase 0.022 ± 0.672 0.020 ± 0.58 0.024 ± 0.80 0.835
 Annual increase in diabetic patients 0.178 ± 0.632 0.098 ± 0.512 0.302 ± 0.780 0.003
Renal
 eGFR baseline (mL/min/1.73 m2) 89.383 ± 16.658 89.542 ± 16.810 89.115 ± 18.190 0.897
 eGFR final (mL/min/1.73 m2) 89.898 ± 18.834 87.891 ± 18.19 93.129 ± 22.07 0.207
 Difference (final–baseline) −1.341 ± 20.100 −2.349 ± 21.253 4.015 ± 16.917 0.022
 Annual increase −0.170 ± 4.945 −0.732 ± 4.698 1.184 ± 5.218 0.104
 Annual increase in diabetic patients −0.308 ± 5.095 −1.286 ± 5.301 1.257 ± 4.406 0.052
Heart
 Cornell VDP baseline (mm/ms) 1604 ± 645 1487 ± 573 1741 ± 598 0.032
 Cornell VDP final (mm/ms) 1568 ± 594 1458 ± 535 1838 ± 740 0.006
 Difference (final–baseline) 36 ± 371 −31 ± 291 97 ± 471 0.229
 Annual increase 12 ± 111 −9 ± 29 31 ± 141 0.206
 Annual increase in diabetic patients 6 ± 101 −8 ± 76 29 ± 131 0.430
  1. Data for qualitative variables are expressed as n: number and (%) and quantitative variables as mean ± standard deviation
  2. Y year, C carotid, IMT intima media thickness carotid, ABI ankle brachial index, PWV pulse wave velocity, eGFR estimated glomerular filtration rate, Cornell VDP cornell voltage duration product, p gender differences