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Table 3 Changes in target organ damage by gender

From: Gender differences in the progression of target organ damage in patients with increased insulin resistance: the LOD-DIABETES study

 

Global

Men

Women

p

n = 112

n = 61

n = 41

Vascular

 C IMT average baseline (mm)

0.775 ± 0.121

0.779 ± 0.127

0.715 ± 0.092

0.003

 C IMT average final (mm)

0.780 ± 0.123

0.796 ± 0.126

0.754 ± 0.115

0.084

 Difference (final–baseline)

0.025 ± 0.077

0.017 ± 0.070

0.039 ± 0.087

0.147

 Annual increase

0.007 ± 0.023

0.005 ± 0.021

0.011 ± 0.025

0.215

 Annual increase in diabetic patients

0.011 ± 0.002

0.007 ± 0.022

0.018 ± 0.027

0.021

 ABI baseline

1.129 ± 0.121

1.116 ± 0.120

1.080 ± 0.109

0.001

 ABI final

1.179 ± 0.107

1.190 ± 0.11

1.160 ± 0.09

0.128

 Difference (final–baseline)

0.049 ± 0.148

0.033 ± 0.155

0.076 ± 0.135

0.142

 Annual increase

0.015 ± 0.044

0.010 ± 0.045

0.022 ± 0.021

0.157

 Annual increase in diabetic patients

0.011 ± 0.042

0.004 ± 0.671

0.021 ± 0.512

0.157

 PWV baseline (m/sec)

9.470 ± 2.467

9.310 ± 2.324

9.740 ± 2.695

0.393

 PWV final (m/sec)

9.594 ± 2.643

9.476 ± 2.472

9.788 ± 2.922

0.507

 Difference (final–baseline)

0.108 ± 2.255

0.146 ± 2.029

0.046 ± 2.603

0.551

 Annual increase

0.022 ± 0.672

0.020 ± 0.58

0.024 ± 0.80

0.835

 Annual increase in diabetic patients

0.178 ± 0.632

0.098 ± 0.512

0.302 ± 0.780

0.003

Renal

 eGFR baseline (mL/min/1.73 m2)

89.383 ± 16.658

89.542 ± 16.810

89.115 ± 18.190

0.897

 eGFR final (mL/min/1.73 m2)

89.898 ± 18.834

87.891 ± 18.19

93.129 ± 22.07

0.207

 Difference (final–baseline)

−1.341 ± 20.100

−2.349 ± 21.253

4.015 ± 16.917

0.022

 Annual increase

−0.170 ± 4.945

−0.732 ± 4.698

1.184 ± 5.218

0.104

 Annual increase in diabetic patients

−0.308 ± 5.095

−1.286 ± 5.301

1.257 ± 4.406

0.052

Heart

 Cornell VDP baseline (mm/ms)

1604 ± 645

1487 ± 573

1741 ± 598

0.032

 Cornell VDP final (mm/ms)

1568 ± 594

1458 ± 535

1838 ± 740

0.006

 Difference (final–baseline)

36 ± 371

−31 ± 291

97 ± 471

0.229

 Annual increase

12 ± 111

−9 ± 29

31 ± 141

0.206

 Annual increase in diabetic patients

6 ± 101

−8 ± 76

29 ± 131

0.430

  1. Data for qualitative variables are expressed as n: number and (%) and quantitative variables as mean ± standard deviation
  2. Y year, C carotid, IMT intima media thickness carotid, ABI ankle brachial index, PWV pulse wave velocity, eGFR estimated glomerular filtration rate, Cornell VDP cornell voltage duration product, p gender differences
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Cardiovascular Diabetology

ISSN: 1475-2840