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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Involvement of Rho-associated protein kinase (ROCK) and bone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER) in high glucose-increased alkaline phosphatase expression and activity in human coronary artery smooth muscle cells

Fig. 4

Effects of rosuvastatin and ROCK inhibitors on BMPER mRNA levels. a Rosuvastatin did not inhibit increases in BMPER mRNA expression in aortas of STZ-induced diabetic mice. The values represent the mean ± SEM (n = 9–11). b Rosuvastatin did not change BMPER mRNA levels in HCASMCs. HCASMCs and HUVECs were cultured with rosuvastatin in high glucose-containing media for 2 days. The values represent the mean ± SEM (n = 4). c Fasudil and Y-27632 did not change BMPER mRNA levels in HCASMCs cultured in high glucose-containing media for 5 days. The values represent the mean ± SEM (n = 3). *P < 0.05; ns not significant.

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Cardiovascular Diabetology

ISSN: 1475-2840