| LETO | OLETF | |||||
---|---|---|---|---|---|---|---|
Vehicle | Vildagliptin | Exenatide | Vehicle | Vildagliptin | Exenatide | Vildagliptin + Chloroquine | |
Blood glucose (mg/dl) | 108 ± 5 | 106 ± 6 | 117 ± 12 | 205 ± 25* | 201 ± 13* | 251 ± 17* | 197 ± 22* |
Serum insulin (ng/ml) | 2.5 ± 0.5 | 1.3 ± 0.2 | 3.1 ± 0.9 | 5.8. ± 0.9* | 2.5 ± 0.5†| 1.3 ± 0.8†| 4.1 ± 0.9 |
Serum TC (mg/dl) | 82 ± 5 | 85 ± 5 | 95 ± 4 | 117 ± 3 | 120 ± 6 | 109 ± 12 | 96 ± 7 |