Cardiovascular Diabetology

Table 3 Regional wall LV function in studies 1 and 2

From: Glucagon-like peptide-1 protects against ischemic left ventricular dysfunction during hyperglycemia in patients with coronary artery disease and type 2 diabetes mellitus

Study 1	Pre-DSE			Peak stress			Recovery
Study 1	Control	HHC	P	Control	HHC	P	Control	HHC	P
V_s (cm/s)	4.7 ± 1.7	4.8 ± 1.8	0.10	8.5 ± 3.3	8.6 ± 3.9	0.22	4.1 ± 1.6	4.6 ± 3.1	0.02
Strain (%)	−17.1 ± 6.9	−16.9 ± 7.7	0.46	−15.8 ± 7.0	−15.9 ± 6.9	0.62	−14.3 ± 6.9	−15.3 ± 7.0	0.06
Strain rate (s⁻¹)	−1.1 ± 0.4	−1.1 ± 0.5	0.66	−1.8 ± 0.9	−1.8 ± 0.8	0.89	−1.0 ± 0.5	−1.0 ± 0.5	0.75

Study 2	Control	GLP-1	P	Control	GLP-1	P	Control	GLP-1	P
V_s (cm/s)	4.58 ± 1.62	4.56 ± 1.58	0.82	9.33 ± 3.25	9.78 ± 3.21	0.008	4.46 ± 1.48	5.01 ± 1.67	<0.0001
Strain (%)	−15.18 ± 5.94	−15.06 ± 5.05	0.77	−15.51 ± 5.39	−18.09 ± 6.58	<0.0001	−14.29 ± 5.35	−16.62 ± 5.71	<0.0001
Strain rate (s⁻¹)	−1.04 ± 0.36	−1.06 ± 0.35	0.50	−2.02 ± 0.71	−2.30 ± 0.75	<0.0001	−0.96 ± 0.31	−1.18 ± 0.36	<0.0001

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ISSN: 1475-2840

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