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Table 1 Muscle content of AICAR and ZMP

From: Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

 

AICAR (n = 7)

Insulin + AICAR (n = 4)

AICAR

ZMP

AICAR

ZMP

(mmol/g wet wt)

(mmol/g wet wt)

Soleus

161 ± 9

325 ± 31

152 ± 22

237 ± 33

Plantaris

116 ± 11*

252 ± 29

116 ± 17

207 ± 43

GW

98 ± 16*

170 ± 27*

86 ± 12

145 ± 25

GR

86 ± 7*

174 ± 30*

110 ± 13

188 ± 23

  1. Muscle content of AICAR and ZMP from AICAR and insulin + AICAR treated animals determined at t = 120 min. Values are mean ± SE.
  2. GW Gastrocnemius white, GR Gastrocnemius red.
  3. * AICAR and ZMP values significantly different (p < 0.05) from soleus values.
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Cardiovascular Diabetology

ISSN: 1475-2840