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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Cardiospecific CD36 suppression by lentivirus-mediated RNA interference prevents cardiac hypertrophy and systolic dysfunction in high-fat-diet induced obese mice

Fig. 3

Phenotype of heart. a Gross appearance of a representative heart from each group. HFD induced visually cardiac hypertrophy compared to CND. Excised hearts were arrested in diastole with 10 % KCl. b Gross heart weight and heart/BW ratio revealed significant increase with HFD compared to CND. Cardiospecific CD36 inhibition significantly decreased heart/BW ratio. BW: body weight. Values are mean ± SD, N = 8 for each group. a, vs. N-mock; b, vs. N-CD36; c, vs. O-mock; (*) P < 0.05

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