Table 1 Clinical and biochemical characteristics of the study patients
Parameters | All patients (n = 212) | Men (n = 107) | Women (n = 105) | P Value (Men vs Women) |
|---|---|---|---|---|
Age, year | 54.1 ± 8.5 | 52.6 ± 9.7 | 55.6 ± 6.9 | 0.011 |
Family history of cardiovascular diseases, % | 45.8 | 43.9 | 47.6 | 0.589 |
Current/past smoker, % | 38.2 | 70.1 | 5.7 | <0.001 |
Body mass index, kg/m2 | 24.5 ± 2.8 | 24.9 ± 2.7 | 24.2 ± 2.8 | 0.069 |
Waist circumference, cm | 87.2 ± 8.2 | 89.1 ± 8.2 | 85.2 ± 7.8 | 0.001 |
Central obesity, % | 52.8 | 34.6 | 71.4 | <0.001 |
Fasting glucose, mmol/L | 7.8 ± 3.3 | 7.6 ± 2.5 | 8.1 ± 3.9 | 0.236 |
HbA1c, % | 7.7 ± 2.4 | 7.8 ± 2.3 | 7.7 ± 2.5 | 0.736 |
Fasting insulina, mIU/L | 13.3 (9.0–19.0) | 14.0 (9.3–18.0) | 12.1 (9.0–21.0) | 0.806 |
Systolic blood pressure, mm Hg | 119.1 ± 17.2 | 116.7 ± 15.6 | 121.5 ± 18.5 | 0.046 |
Diastolic blood pressure, mm Hg | 76.6 ± 10.7 | 77.1 ± 10.4 | 76.1 ± 11.0 | 0.488 |
Hypertension, % | 23.1 | 19.6 | 26.7 | 0.224 |
Triglyceridesa, mmol/L | 1.62 (1.16–2.53) | 1.87 (1.24–3.31) | 1.51 (1.11–2.07) | 0.001 |
Low-density lipoprotein-cholesterol, mmol/L | 3.1 ± 1.0 | 3.0 ± 1.1 | 3.1 ± 0.9 | 0.501 |
High-density lipoprotein-cholesterol, mmol/L | 1.3 ± 0.4 | 1.2 ± 0.4 | 1.4 ± 0.3 | <0.001 |
Dyslipidemia, % | 73.1 | 72.9 | 73.3 | 0.943 |
Carotid intima-media thickness, mm | 0.75 ± 0.20 | 0.75 ± 0.19 | 0.75 ± 0.21 | 0.955 |
Femoral intima-media thickness, mm | 0.77 ± 0.23 | 0.75 ± 0.18 | 0.79 ± 0.27 | 0.217 |
Iliac intima-media thickness, mm | 0.85 ± 0.22 | 0.85 ± 0.23 | 0.85 ± 0.21 | 0.953 |
Subclinical atherosclerosis, % | 20.8 | 19.6 | 21.9 | 0.683 |
Fibroblast growth factor 21a, ng/L | 154.0 (105.6–283.3) | 142.4 (86.1–269.8) | 175.9 (125.1–309.0) | 0.137 |